Which layer of the skin is involved in intradermal medication administration?

The dermis is the correct layer of the skin involved in intradermal medication administration because it contains a rich supply of blood vessels, nerves, and immune cells, making it an ideal site for the absorption of medications. Intradermal injections are administered just beneath the epidermis and into the upper part of the dermis, allowing for a slow and controlled release of the medication, as well as localized reactions which are often necessary for certain testing or treatments, such as allergy tests or tuberculin skin tests.

The dermis also supports the epidermis and plays a crucial role in skin health and function, which is why targeting this layer is effective for delivering specific medications. The other skin layers—epidermis, subcutaneous layer, and hypodermis—do not provide the same level of absorption capability or appropriate environment for intradermal delivery, thereby affirming the dermis as the correct choice for this method of medication administration.