What effect do nonsteroidal anti-inflammatory drugs (NSAIDs) have on the body?

Nonsteroidal anti-inflammatory drugs (NSAIDs) primarily function by inhibiting the production of prostaglandins, which are chemicals in the body involved in inflammation, pain, and fever. By reducing prostaglandin synthesis, NSAIDs effectively lower body temperature, making option C the correct choice. This antipyretic effect is particularly important in treating conditions like fever, where the aim is to bring down elevated body temperature.

The impact of NSAIDs on body temperature is due to their action on the hypothalamus, the part of the brain that regulates temperature. When prostaglandin levels are reduced, the hypothalamus can adjust and lower the thermoregulatory setpoint, leading to a decrease in temperature.

Other options relate to effects that are not typically associated with NSAIDs. For instance, NSAIDs do not increase cough reflex or sedation, nor do they induce pain sensation. Rather, they are used to manage pain and inflammation, making their primary role counter to inducing pain.